Resveratrol Supplements and Anti-Aging
Resveratrol, an ingredient found in the
skin of red grapes and red wine, has been proven to both
reverse the effects of obesity in mice and extend their
lifespan. More recent studies are showing that resveratrol also
increases their endurance.
Ordinary mice will typically run
approximately one kilometer on a treadmill before collapsing in
exhaustion. However, mice given a resveratrol supplement will
run twice as far before showing any evidence of tiring. In
addition, tests show that these mice have enhanced muscular
energy and a significantly reduced heart rate, similar to the
qualities found in trained athletes.
Doctors at the Institute of Genetics and
Molecular and Cellular Biology in Illkirch, France have
completed initial human experiments that demonstrate that
similar results can be obtained in human test subjects that are
placed on a program of high quality resveratrol
supplementation.
Resveratrol Generates Energy
The key to resveratrol's effects on the
body are in the substances ability to work at a cellular level
to increase the production of mitochondria. Mitochondria are
the organisms in the body that generate energy. The extra
mitochondria in the treated mice resulted in the ability to
burn more fat and to optimize muscle functions.
Dr. Ronald M. Evans, a scientist at the
Salk Institute and an expert on the hormonal control of
metabolism, said the report by the French genetics team had
"shown very convincingly that resveratrol improves
mitochondrial function" and wards off metabolic disease. Evans
described the study as "very important, because it is rare that
we identify orally active molecules, especially natural
molecules, that have such a broad-based, positive effect on a
problem which is as widespread in society as metabolic
disease."
A drug that prevents degenerative
disease, prolongs life, and can reshape an individual into a
champion athlete sounds almost too good to be true. But doctors
are convinced that their work into the effects of resveratrol
have led to some surprising advancements in the area of
anti-aging. They now believe that the body's ability to utilize
sirtuins, enzymes that protect and energize our systems,
declines with age. This is the process that is reversed by
resveratrol.
The growing evidence supporting the
power of resveratrol has infected scientists who do research on
the aging process, several of whom are already taking
resveratrol. Dr. David Sinclair, a scientist at the anti-aging
drug research company Sirtris, has been swallowing resveratrol
supplement capsules for three years and has claimed that
his parents and half the members of his laboratory do the
same.
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